Just 45 years ago, 16 states deemed marriages between two people of different races illegal.
But in 1967, the U.S. Supreme Court considered the case of Richard Perry Loving, who was white, and his wife, Mildred Loving, of African American and Native American descent.
The case changed history – and was captured on film by LIFE photographer Grey Villet, whose black-and-white photographs are now set to go on display at the International Center of Photography.